Search results for "TAS2R16 gene"

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Taste receptors, innate immunity and longevity: the case of TAS2R16 gene

2019

Abstract Background Innate immunity utilizes components of sensory signal transduction such as bitter and sweet taste receptors. In fact, empirical evidence has shown bitter and sweet taste receptors to be an integral component of antimicrobial immune response in upper respiratory tract infections. Since an efficient immune response plays a key role in the attainment of longevity, it is not surprising that the rs978739 polymorphism of the bitter taste receptor TAS2R16 gene has been shown to be associated with longevity in a population of 941 individuals ranging in age from 20 to 106 years from Calabria (Italy). There are many possible candidate genes for human longevity, however of the many…

0301 basic medicinelcsh:Immunologic diseases. AllergyCandidate geneAgingmedia_common.quotation_subjectPopulationImmunologyLongevityShort ReportCase control studyGenome-wide association studyBiologylcsh:Geriatrics03 medical and health sciences0302 clinical medicineImmune systemstomatognathic systemTaste receptorGWASReceptoreducationBitter taste receptormedia_commonSettore MED/04 - Patologia GeneraleGeneticsInnate immunityeducation.field_of_studyInnate immune systemLongevitylcsh:RC952-954.6030104 developmental biologyBitter taste receptors; Case control study; GWAS; Innate immunity; Longevity; TAS2R16 gene; Immunology; AgingTAS2R16 geneBitter taste receptorslcsh:RC581-607030215 immunologyImmunity & Ageing : I & A
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